Thursday 31st January 2019

What Is The Entourage Effect?

Published by Canavape® in Canavape® Blog.

Marijuana and hemp are both plants that belong to the same plant species, Cannabis Sativa. Each plant in the species contains hundreds of different compounds, including some well-known ones like CBD and THC, all of which interact with each other and the human body in different ways.

The entourage effect refers to the way that all of these compounds – mainly cannabinoids and terpenes – work in synergy to create a holistic effect on the human body that’s greater than the sum of its parts.

Although CBD may seem like a miracle cure, its effects on appetite, pain-sensation, mood and memory are due to the fact that naturally occurring cannabinoid receptors are spread throughout the human brain and body.

Combined with other cannabinoids such as CBG, however, CBD may be even more effective and could potentially find use as a treatment option for a wider range of physical ailments and mental health conditions.

What are terpenes?

Terpenes are a large group of organic hydrocarbons that give cannabis its aromatic and taste diversity. They are secreted as oils in the flower’s sticky resin glands, the same ones responsible for THC, CBD, and other cannabinoids.

Terpenes are not exclusive to the cannabis family. They can also be found in herbs, fruits and plants. One example of a terpene that is found outside of cannabis is limonene, which produces the zesty fragrance and taste in citrus fruits.

Each cannabis compound influences other compounds around it. Even small amounts of terpenes, such as the presence of the terpene that gives cannabis its smell, can make a difference to the final effect that a cannabis-derived product or medicine can have on an individual.

An example of this is the combination of cannabis compounds myrcene, pinene, and caryophyllene that helps to aid anxiety symptoms. Myrcene is a terpene found in cannabis that cana reduce resistance in the blood-brain barrier which means other beneficial chemicals can pass through more easily. Pinene helps counteract compromised cognition and memory caused by THC, and caryophyllene has anti-inflammatory properties.

While individually, these compounds have beneficial effects, together they create a combined effect that is much more comprehensive and suitable for treating anxiety symptoms.

The entourage effect’s potential

CBD-only medicines are known for treating a lot of conditions, but when combined with their other natural compounds such as CBG, CBN, CBC and THC, the possibilities for treatment are greater.

However, full spectrum oil is not always the best solution for sufferers, as tailored formulations can be much more effective. GFarma News writes that “whole-plant consumption effectively throws an unknown and unquantified combination of cannabinoids at every receptor and hopes for the best. It is the ultimate in polypharmacology. The other side of the coin is using a single cannabinoid to target a single receptor like CB-1 (cannabinoid receptor 1) to perform a single activity. This is the approach taken by Big Pharma thus far, ignoring the entourage effect altogether.”

Additionally, some cannabis compounds don’t work well synergistically, and can even block each other from working effectively if both present in the same product, so it’s not always ideal to have a full spectrum of cannabinoids and terpenes if you’re looking for specific targeted relief.

Canavape’s CBD oil contains CBG, a cannabinoid which has been proven to have similar properties to CBD. When working together, these two cannabinoids can be even more effective. Canavape Complete E-Liquid contains CBD, CBG, and terpenes from different strains of cannabis plants, so it provides a fuller entourage effect.

How you choose to take CBD depends on the symptoms you wish to alleviate. Always do your research and work out the correct dosage that will bring the desired results for you.

Last updated: Tuesday 05th March 2019